Article
Outpatient hysteroscopy comes to the H.U.B!
The Department of Gynaecology recently inaugurated a new fully equipped unit dedicated to outpatient hysteroscopy at the Erasmus Hospital. The H.U.B is the third French-speaking centre in Belgium to propose this operative procedure during consultations for patients with abnormal uterine bleeding due to an intracavitary pathology. Dr. Ludovica Imperiale, gynaecologist specialised in minimally invasive surgery and head of the H.U.B Bleeding Clinic, discusses the benefits of offering such an integrated approach to hysteroscopy. Interview with Dr. Ludovica Imperiale What is the nature of the treatment pathway of a patient who is to undergo a hysteroscopy?Normally we propose a hysteroscopy to patients with a potential pathology of the uterine cavity, such as fibriols, polyps or endometrial cancer. It can also be proposed to patients who have given birth or had a miscarriage and who have retained placenta. The point in common between all these pathologies is that they cause abnormal uterine bleeding  in the patients. That is why a hysteroscopy is a procedure carried out at the H.U.B’s Bleeding ClinicThe treatment pathway first involves an appointment with a gynaecologist who carries out a full examination and an ultrasound so as to view the uterus in its entirety. If necessary, a diagnostic hysteroscopy can be carried out during the  consultation to confirm the pathology. If the diagnostic hysteroscopy identifies an intracavitary pathology the patient returns for a second consultation for an operative hysteroscopy to treat the lesions in the uterusMost hospitals perform an operative hysteroscopy in the operating room as the procedure requires dilation of the uterus, a painful procedure that must be done under an anaesthetic. The H.U.B is the third hospital in French-speaking Belgium to propose an operative hysteroscopy during a consultation and to have acquired TruClear®, a leading edge technology developed by the Medtronic company that, thanks to its small size, makes it possible to remove polyps or any other intracavitary pathology, in most cases without pain or bleeding and without anaesthetic. This is a truly major innovation for patients who, after this painless and rapid procedure, are rapidly able to resume their day’s activities without the least side effect.  It should be stressed that an outpatient hysteroscopy is recommended in particular for “minor” pathologies. It is not a procedure that can be proposed to all patients. Operative hysteroscopy will be proposed to patients for whom the diagnostic hysteroscopy was painless and with a benign intracavitary pathology. Of course if these patients prefer a procedure under anaesthetic this solution remains accessible.  This outpatient approach is also interesting for the hospital in the sense that not using the operating rooms for hysteroscopies frees them for other procedures at the Day Hospital, thereby reducing waiting times for patients.  How do the new unit and new equipment facilitate the treatment pathway?Everything is done at a single location, at a consultation. In the new unit we have equipped for this we have a 3D ultrasound machine and instruments to carry out diagnostic hysteroscopies and, if necessary, biopsies.  We also have a TruClear® system  that is available for outpatient operative hysteroscopies as well as virtual reality headsets for hypnosis during the procedure. Also, this unit is adjacent to the Day Hospital which means, in the case of any complication, we have rapid access to the operating room. A specialised nurse, Mme Émilie Chasseriaud, is also on hand to accompany the doctors and patients during the procedure.    What expertise does the H.U.B have in this field?The H.U.B has real expertise in this field with a team of 6 gynaecologists from the Gynaecology Clinic (myself, Dr. Soria, Dr. Vanneste and Dr. Zingarelli) and from the Fertility Clinic (Dr. Moutard and Dr. Rabattu). We are all specialised in  minimally invasive surgery and trained in the procedure. Together, we carry out 500 diagnostic hysteroscopies and 200 operative hysteroscopies a year.MAR is another field in which hysteroscopy certainly has a place as patients who go to the Fertility Clinic often need an examination that includes an examination of their intrauterine cavity before commencing their MAR treatment.The Department of Haematology  is also integrated in the Bleeding Clinic treatment pathway so as to rule out coagulation disorders as being the cause of abnormal uterine bleeding  in a patient or to treat iron deficiency anaemia caused by abundant bleeding.  What message would you like to give to gynaecologists and GPs?  The H.U.B now proposes a consultation that is completely integrated in outpatient hysteroscopy at the Erasmus Hospital every day with short waiting times. We can act rapidly in treating patients with:•    Abnormal uterine bleeding during or between periods;•    Abnormal uterine bleeding in menopausal women;•    Iron deficiency anaemia with no evident cause identified in a blood test;For any urgent request for an appointment or opinion for a patient, the gynaecology consultation can be contacted directly  by mail to Cons [dot] Gyn-Obs [dot] erasme [at] hubruxelles [dot] be (Cons[dot]Gyn-Obs[dot]erasme[at]hubruxelles[dot]be)   Contact and information Dr. Ludovica ImperialeHead of the H.U.B Bleeding Clinicludovica [dot] imperiale [at] hubruxelles [dot] be (ludovica[dot]imperiale[at]hubruxelles[dot]be) 
Health issues
Pancreatic cancer
What is pancreatic cancer? Pancreatic cancer is the 4th cause of cancer deaths. In recent years the incidence of pancreatic cancer has continued to increase and today it accounts for 10-12 cases/100,000 persons. Pancreatic cancer develops from pre-cancerous lesions some of which are in the form of pancreatic cysts. Together with certain family factors, risk factors for this cancer are smoking, diabetes, alcohol consumption and obesity.   Care At our institutions we have developed a Fast Track care pathway for screening/diagnosing pancreatic cancer in all persons presenting a clinical (unexplained weight loss, jaundice, abdominal pain, decompensated diabetes) or radiological suspicion of cancer as well as for persons screened who are  at increased risk of pancreatic cancer (family history, chronic hereditary pancreatitis).  Following a pancreatic cancer diagnosis a complete medical check-up is carried out and the results discussed at a multidisciplinary meeting so as to decide on the line of treatment. If the pancreatic cancer is considered to be localised and resectable, pancreatic surgery can be envisaged, possibly  following  induction treatment (chemotherapy +/- radiotherapy). If it is non-resectable or metastatic, chemotherapy is proposed, possibly in the framework of study protocols. In Belgium, pancreatic surgery has been centralised since July 2019 at 15 experienced hospitals (including 6 French-speaking hospitals) with a high volume of pancreatic interventions so as to improve the care quality. The Erasmus Hospital is the leading French-speaking hospital in terms of the annual number of pancreatic surgery operations.     Research The HUB is active in developing new treatment approaches and initiated a multicentric study ((STEREOPAC) to assess the impact of stereotaxic radiotherapy (radiotherapy targeted at the tumour) following neoadjuvant chemotherapy in the case of localised pancreatic cancer .The Digestive Oncology Department is linked to the Laboratory of Experimental Gastroenterology (LGE) of the ULB’s Faculty of Medicine and to the Jules Bordet Institute’s GI Lab where a number of research projects are carried out, in particular on the immune-molecular impact of pancreatic cancer treatment.   A number of our doctors are members of various national and international groups of experts, namely :  the Belgian Group of Digestive Oncology, the Belgian Pancreatic Group, the Belgian Pancreatic Cancer Group, the European Society of Digestive Oncology and the European Society of Gastrointestinal Endoscopy. Our specialists Image Multidisciplinary bilio-pancreatic pathology group Associated services Publications Preoperative treatment with mFFX or GemNab and iHDSBRT (STEREOPAC trial) Authors : Bouchart et al Journal : BMC Cancer NAC associated with iHD-SBRT does not increase complications after PD Authors : Navez J et al Journal : J Surg Oncol Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features Authors : Puleo et al Journal : Gastroenterology Assessment of response to chemotherapy in pancreatic ductal adenocarcinoma: Comparison between diffusion-weighted MR quantitative parameters and RECIST Authors : Bali et al Journal : Eur J Radiol
Pancreatic cancer
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Parkings
There are two supervised car parks, managed by an external company. There is also parking in the neighbouring streets (route de Lennik, motorway access road and industrial estate)Erasmus car park: Covered - Open 24h/24h. Payment point 5 in the Bucopa gallery accepts Bancontact, Maestro, Mastercard and Visa payment cardsLennik car park: Open Monday to Friday, from 6.30 am to 10.30 pm. Closed weekends and public holidaysThese car parks can be accessed from exit 15a without entering the Low Emission Zone (LEZ - see LEZ map). Image Tarifs "Erasmus" car parkDuration"Lennik" car park" /30 min/2,70 € 1h1,50 €5,50 €2h3,30 €8,30 €3h4,50 €11,10 €4h6,00 €13,90 €5h6,00 €16,70 €6h6,00 €18,00 €7h – (7 to 24h)6,00 €18,00 €8h 6,00€18,00 €9h6,00€18,00 €10h - 24h6,00€/1 day//Weekend rate/Weekly rate:€55//Monthly rate: €145//Lost ticket10 €10 €  A car park for emergencies and a car park in front of the Day Hospital are also accessible for persons visiting these units.  There are two supervised car parks, managed by an external company.
Health issues
Parkinson’s disease and Abnormal Movements Clinic
What is Parkinson’s disease? Parkinson’s disease is a common neurodegenerative disease, the second most common after Alzheimer’s. It is caused by a lack of the neurotransmitter dopamine that is present deep in the brain. Parkinson’s is estimated to affect some 30,000 people in Belgium, which is about 2.5 people for every 1,000 inhabitants. Parkinson’s disease is slightly more prevalent among men than women. The causes remain unclear and complex genetic and environmental factors are no doubt involved. Typical signs of Parkinson’s are resting tremors, stiffness and slowness of movement. There can also be non-motor symptoms that may affect sleep, behaviour or memory for example. Treatment Neurologists can prescribe medication. This does not treat the disease itself but is effective in alleviating symptoms. Physiotherapy can also play an important role in maintaining a good physical condition. A complete physiotherapy assessment can be carried out in cooperation with the Centre for Adult Neurological Functional Rehabilitation. At an advanced stage of the disease, deep brain stimulation  may be proposed in cooperation with the Department of Neurosurgery, especially for persons  aged under 70. Other persons can benefit from pump treatment that introduces medication into the digestive tract. This is carried out in cooperation with the Department of Gastroenterology.    Other diseases Certain rare diseases can resemble the early stages of Parkinson’s disease. Neurologists will draw on their expertise to detect specific signs of these diseases that are known as  Parkinson-plus syndromes and they will make the differentiation, often in cooperation with the Departments of Diagnostic Neuroradiology, Nuclear Medicine and in association with neuropsychologists.   Not all tremors indicate Parkinson’s. Essential tremor is a disease that can be distinguished by the fact that the trembling is the only symptom and is distinctive in that it occurs when making certain movements, such as eating, drinking or brushing your teeth. It is often overlooked despite the fact that it is probably more common than Parkinson’s disease. It can be treated very effectively with medication and more rarely with neurosurgery.   Dystonia is a neurological disease resulting in an abnormal muscle tone caused by a bad signal sent by the brain. Persons with dystonia suffer from involuntary muscle contractions. This causes abnormal posture or movements, such as torticolis, writer’s cramp and blepharospasm (involuntary contraction of the eyelid muscles). It can also be generalised, confining patients  to a wheelchair or distorting  the skeleton. It can affect people of any age, including children. Treatment is by medication, especially botulinum toxin injections, and sometimes by neurosurgery with deep brain stimulation.   Huntington’s disease is a neurodegenerative disease characterised by involuntary movements that are called chorea, cognitive disorders and behavioural disorders. It is transmitted by parents to the children with a 50% risk of transmission. A simple genetic test gives a diagnosis with 100% certainty. There is worldwide registration of Huntingdon’s disease, on the  Enroll-HD research platform to which we contribute, and that operates as a gateway to possible clinical trials. Treatment is for the symptoms only and of limited effectiveness although progress in recent years is encouraging.  Other pathologies are also treated:   restless leg syndrome, Gilles de la Tourette syndrome, paroxymal dyskinesia, orthostatic tremors, etc.   Our specialists Related service
Parkinson’s disease and Abnormal Movements Clinic
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